Opioid Induced Constipation

If you take a prescription opioid medication and suffer from constipation, we would like to hear from you. The goal of this investigational treatment for opioid constipation is to reduce constipation while preserving the effects of opioid therapy. Constipation is the hallmark of this syndrome. However, this investigational treatment may also help opioid induced bowel dysfunction, a condition that may also include other symptoms like bloating, abdominal cramping and gastroesophageal reflux.

Our clinic is conducting a research study to evaluate an investigational drug, for opioid-induced constipation (OIC) in men and women with non-cancer related pain.


You may be able to participate if you are:

  • between 18 and 80 years of age
  • taking at least one prescription opioid pain medication daily (vicodin, oxycontin, percocet)
  • experiencing constipation symptoms such as-
  • fewer than three bowel movements per week
  • hard/lumpy stools
  • straining
  • sensation of incomplete bowel movement


All office visits, study-related medical evaluations, and investigational drug will be provided to study participants at no cost. Participants will be paid for their study related time and travel.

For more information please contact: Clinical Study Center at 239-936-4421