Our History

The Alliance for Multispecialty Research was founded in 1994 to serve as a hub for shared marketing, business development, and best practices for elite clinical research centers. Exclusive membership was determined by rigorous peer review, revenue and quality requirements, geographic location, and therapeutic expertise.

In 2017, 15 AMR centers merged their businesses to form a single company. Two additional centers elected to remain independent but aligned operations and function seamlessly as AMR members. The new AMR now includes 17 locations across the continental United States, 126 investigators, and access to databases of over 657,344 patients. As one company, AMR now offers improved efficiencies with the same exceptional quality and industry professionals you trust.

Our Company

AMR performs phase I, II, III, and IV clinical research trials to support pharmaceutical companies in the development of new drugs, devices, and vaccines at 17 locations across the United States. Over 24 years ago, AMR owners began collaborating based on their mutual respect and shared values. Relationships are the foundation of AMR’s success. Our flexible solutions propel clinical trials from ideas to reality through relationships with industry experts you know.

AMR The Alliance for Multispecialty Research
Center Relationships: AMR evolved through personal relationships that empower our investigators to collaborate and offer sponsors responsive solutions possible only through their deep shared history.
AMR The Alliance for Multispecialty Research

Industry Relationships AMR is proud to partner with the largest, most reputable companies in the industry. Over 80% of our business comes directly from established relationships with CROs and Sponsors.

AMR The Alliance for Multispecialty Research
Subject Relationships: AMR’s diverse volunteers keep coming back and encourage their friends to participate because of trusted relationships with our staff and the quality, compassionate care they provide.


These solid relationships form the foundation of our company and empower AMR centers to consistently provide accurate results on-time. Collectively AMR investigators have:

  • Completed over 7,749 Clinical Trials
  • Enrolled over 145,552 Subjects
  • Partnered with over 560 Sponsors and CROs
  • Achieved an Average Enrollment Rate of 110%
  • Realized an Average Retention Rate of 92% across all Therapeutic Areas

Our Certifications

AMR centers and staff maintain the following accreditations, certifications and licenses:

  • ACRP Certified Coordinators (varies by location)
  • American Heart Association Certification for Standards and Techniques of Blood Pressure Measurements
  • Bio-Safety Level 1 and 2
  • BNDD Licenses
  • Certified Clinical Research Coordinators
  • Certified Principal Investigator (CPI)
  • Certified Smoking Cessation Counselors
  • CLIA Certified Laboratories
  • Controlled Substance Licenses
  • CPR/BLS Certified Staff
  • FAA Certification for the Shipment of Hazardous Materials
  • Federal Wide Assurance Numbers
  • GDUFA Registration
  • HIPAA Compliant
  • IATA Certified
  • NIH and CITI Certifications
  • Registered Dietitians

Our Leadership



Dr. William Smith is the Founder, President, and Principal Investigator of VRG and NOCCR, the AMR centers in Knoxville, TN and New Orleans, LA. He is also one of the original founders of AMR. Dr. Smith is board certified in Internal Medicine, Critical Care Medicine, Nephrology, and Cardiology. He has been involved in more than 1,700 clinical trials over the past 35 years. He is a frequent lecturer and author and publishes extensively.


Dr. Terry Poling is board certified in Family Medicine and started his private practice after serving in the Air Force as a flight surgeon. He began conducting clinical research trials in 1991. He is an Associate Clinical Professor at the University of Kansas School of Medicine. Dr. Poling founded Heartland Research Associates in 1994 with five dedicated research centers located in Wichita, KS and the surrounding area and has been involved in over 1,392 trials. Heartland Research Associates joined AMR in 2000.


Dr. Jeffrey Rosen is the Medical Director of Clinical Research of South Florida. He has been conducting clinical research for 34 years and has been involved in more than 800 clinical trials. Dr. Rosen is a founding member of AMR and is on the Leadership Council for the Society for Clinical Research Sites. He has been a speaker at many research conferences and for several pharmaceutical companies.

Debbie Dyer, RN, BSN, Regional Vice President

Ms. Dyer currently serves as the Regional Vice President of AMR’s Eastern Division. She is the co-founder of AMR Lexington, previously Central Kentucky Research Associates (CKRA). Debbie and her business partner, the late Jacquie Smith, launched CKRA in 1991. For more than 25 years, they built a responsive and respected organization that consistently delivered results. Debbie holds a BSN from Eastern Kentucky University College of Allied Health and Nursing and holds an active nursing license from the state of Kentucky. She has more than 25 years of experience in clinical trials and is a well-respected figure in the industry. Debbie has been recognized as “Small Businessperson of the Year” for the State of Kentucky by the U.S. Small Business Administration.


For nearly two decades, Mr. Stone has served in senior executive roles, primarily as a Chief Financial Officer or Chief Operating Officer. A Certified Public Accountant, he has broad and deep experience working with both public and private companies across an array of industries, including technology, healthcare, telecommunications, and manufacturing. Other experience includes capital strategies.

Jesse Hoffman, Chief Business Officer

Mr. Hoffman has more than 15 years of clinical research experience, working at a leading CRO and site organization. There, he served in a variety of leadership and business development roles. Jesse joined PharmaNet in 2007, which through several M&A transactions became Syneos Health, a top global CRO. Before joining PharmaNet, he served as President at Advanced Clinical Research, a previous member of AMR, with research centers in Utah and Idaho.

Our Experts


Kevin Fleishman, MD, FACOG

Dr. Kevin Fleishman, MD, FACOG is an experienced board-certified obstetrics and gynecology physician at Premier Women’s Care of Southwest Florida, located in Fort Myers. He holds degrees in biology and psychology from Duke University, received his medical degree from the University of Maryland School of Medicine, Baltimore and did his residency at Eastern Virginia Graduate School of Medicine, Norfolk, Virginia.

Natasha Bower, MD, FACOG

Dr. Natasha Bower, MD, FACOG is a board-certified obstetrics and gynecology physician at Premier Women’s Care of Southwest Florida, located in Fort Myers. She holds her undergraduate degree from Florida Atlantic University, Boca Raton, received her medical degree from the University of Miami Leonard M. Miller School of Medicine in Miami and completed her residency training at the University of Vermont Fletcher Allen Health Center in Burlington, Vermont.

Robert Pritt, DO 

Dr. Robert Pritt has been in private family medical practice in Fort Myers, Florida for more than 20 years and has also been a medical director for a number of retirement centers in central Florida. He holds a MS in Biology from Frostburg State University and a DO from the West Virginia School of Osteopathic Medicine.

Greg Flinders, PA-C

Physician’s Assistant Greg Flinders has been practicing in Fort Myers for 11 years, the past 3 with Dr. Robert Pritt in his family practice office. He holds a BS in Science from Hodges University and a master’s in physician assistant from Nova Southeastern University.

Pedro Ylisastigui, MD

Dr. Ylisastigui, MD has been in private family medicine practice in the Fort Myers area for more than a decade and been involved in clinical research for the past 25 years. He holds an MD from the Higher Institute of Medical Sciences of Havana, Cuba and has advanced Clinical Pharmacology training from the Institute as well as from the University of Heidelberg in Heidelberg, Germany.  Dr. Ylisastigui completed his Internal Medicine Residency Training at the university of North Dakota in Fargo, ND and has extensive phase I – IV PI experience.

Aurora Badia, MD, DO, FAAD

Dr. Anais Aurora Badia, M.D., D.O., F.A.A.D., a board-certified Dermatologist and Pediatrician founding the Florida Skin Center in 2001.  Her main office is directly across the street from AMR Fort Myers. She holds a BS from the University of Miami, a DO from the Nova Southeastern College of Osteopathic Medicine, a MD from the University of Health Sciences School of Medicine and completed dermatology training in Albany, New York.

Shirisha Vallarapu, PA-C

Shirisha Vallarapu is a board-certified physician assistant and has achieved Diplomate Status from the Society of Dermatology Physician Assistants.  She holds a BS in Microbiology from Miami University and BS and Master’s of Medical Science Physician Assistant Studies from Nova Southeastern University.

Linda Aschom, BSN, ARNP, CRNA

Linda Aschom is the former owner of AMR Fort Myers and has extensive healthcare experience in nursing and as a Nurse Anesthetist over the past 35 years. She holds a BS degree in Chemistry/Physics, a BSN in Nursing from Murray State University, Murray, KY and has a CRNA degree from the Southwest Missouri School for Nurse Anesthesia, Springfield MO.


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